Article

Comparison of the Diagnostic Significance of CSF Metagenomic Next-generation Sequencing Copy Number Variation Analysis and Cytology in Leptomeningeal Malignancy

2023-08-05

Abstract excerpt

<h4>Purpose: </h4> The early diagnosis of leptomeningeal malignancy remains a formidable challenge in clinical practice. This study aimed to investigate the diagnostic potential of CSF metagenomic next-generation sequencing (mNGS) and chromosome copy number variations (CNVs) analysis in the detection of leptomeningeal malignancy. The diagnostic significance of mNGS-CNVs was compared with that of cytology. Methods...

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Literature Corpus work: 3b5c69e4-993a-5450-a64e-53607e9b11d9
DOI: 10.21203/rs.3.rs-3216228/v1

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