Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy number variation analysis of cerebrospinal fluid metagenomic next‐generation sequencing data in assisting the diagnosis of pediatric brain tumors

31 Jul 2026

Abstract excerpt

Pediatric central nervous system (CNS) malignancies are rare but represent the leading cause of cancer-related mortality in children. 1 Early diagnosis is crucial for improving prognosis, yet it remains challenging because CNS malignancies, infections, and inflammatory syndromes often present with overlapping clinical and radiologic features.Cerebrospinal fluid (CSF) cytology has low sensitivity due to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomic variations and chromosomal abnormalities
Share to Genomics and Rare Diseases
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 42540776
DOI: 10.1002/ped4.70076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy number variation analysis of cerebrospinal fluid metagenomic next‐generation sequencing data in assisting the diagnosis of pediatric brain tumorsPMID 42540776Read ↗

Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal FluidSemantic proximity Read ↗

Comparison of the Diagnostic Significance of Cerebrospinal fluid Metagenomic Next-generation Sequencing Copy Number Variation Analysis and Cytology in Leptomeningeal MalignancySemantic proximity Read ↗

Low-Pass Whole Genome Sequencing of Cell-Free DNA from Cerebrospinal Fluid: A Focus on Pediatric Central Nervous System TumorsSemantic proximity Read ↗

Comparison of the Diagnostic Significance of CSF Metagenomic Next-generation Sequencing Copy Number Variation Analysis and Cytology in Leptomeningeal MalignancySemantic proximity Read ↗

Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult brain tumor patients.Semantic proximity Read ↗

Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.Semantic proximity Read ↗

Evaluating Infectious, Neoplastic, Immunological, and Degenerative Diseases of the Central Nervous System with Cerebrospinal Fluid-Based Next-Generation Sequencing.Semantic proximity Read ↗

Exploring genetic alterations in circulating tumor DNA from cerebrospinal fluid of pediatric medulloblastoma.Semantic proximity Read ↗

Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAMSemantic proximity Read ↗

Evaluating the clinical utility of genomic profiling using cerebrospinal fluid to inform treatment and management of central nervous system tumors – a Meta Analysis of the literatureSemantic proximity Read ↗

Cerebrospinal Fluid from Cytology Supernatant as a Liquid Biopsy Specimen for Diagnosis and Surveillance for Pediatric Primary Central Nervous System TumorsSemantic proximity Read ↗

Detection of tumor-derived cell-free DNA in cerebrospinal fluid using a clinically validated targeted sequencing panel for pediatric brain tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.