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Evaluating the Cerebrospinal Fluid ctDNA detection by Next-Generation Sequencing in the diagnosis of Meningeal Carcinomatosis

2019-10-14

Abstract excerpt

<title>Abstract</title> <p>Background Meningeal carcinomatosis (MC) is the most severe form of brain metastasis and causes significant morbidity and mortality. Currently, the diagnosis of MC is routinely confirmed on the basis of clinical signs and symptoms, positive cerebrospinal fluid (CSF) cytology, and/or neuroimaging (contrast-enhanced brain MRI and/or CT) features. However, negative rate of CSF cytology an...

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Literature Corpus work
f3822710-3a60-5a75-a188-a4c4d58e65dd
DOI
10.21203/rs.2.9575/v2
Open publication

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Evaluating the Cerebrospinal Fluid ctDNA detection by Next-Generation Sequencing in the diagnosis of Meningeal CarcinomatosisDOI 10.21203/rs.2.9575/v2
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