Article

p53-induced GDF-15 expression promotes a pro-regenerative response in human chondrocytes upon cartilage injury

2024-04-11

Abstract excerpt

Posttraumatic osteoarthritis (PTOA) is a special form of OA, developing after joint injuries. Except for some minor differences between the clinical characteristics of patients suffering from idiopathic OA (IOA) and PTOA, no biologic marker has yet been identified to distinguish IOA from PTOA. In this study, we investigated the expression of the stress-responsive cytokine growth differentiation factor 15 (GDF-15)...

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Literature Corpus work: e7761734-71fc-57ee-8c34-ba25f27e5f64
DOI: 10.1101/2024.04.10.588843

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