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Article

GDF15 as a key disease target and biomarker: linking chronic lung diseases and ageing

24 Apr 2023

Abstract excerpt

Growth differentiation factor 15 (GDF15), a member of the transforming growth factor-beta superfamily, is expressed in several human organs. In particular, it is highly expressed in the placenta, prostate, and liver. The expression of GDF15 increases under cellular stress and pathological conditions. Although numerous transcription factors directly up-regulate the expression of GDF15, the receptors and downstream...

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PMID: 37093513
DOI: 10.1007/s11010-023-04743-x

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