Article

Parental lifespan and polygenic risk score of longevity are associated with white matter hyperintensities

2021-02-05

Abstract excerpt

Human longevity is moderately heritable and is hence influenced by both genetic and environmental factors. However, there remains considerable uncertainty regarding its relationship with brain ageing. In this study, we investigated the associations of parental lifespan (parental age at death) and polygenic risk score for longevity (longevity-PRS) with structural magnetic resource imaging (MRI) brain metrics consid...

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Literature Corpus work: e72f1155-3136-5835-be99-40350427514c
DOI: 10.1101/2021.02.02.21251026

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