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Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer’s disease in the UK Biobank

2023-10-20

Abstract excerpt

During the course of adulthood and ageing, white matter (WM) structure and organisation are characterised by slow degradation processes such as demyelination and shrinkage. An acceleration of such ageing process has been linked to the development of a range of diseases. Thus, an accurate description of healthy brain maturation, in particular, in terms of WM features, provides a cornerstone in the understanding of...

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Literature Corpus work
6fe1d44b-1ab3-5b96-b85c-0f30fe89dcd8
DOI
10.1101/2023.10.19.23297257
Open publication

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Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer’s disease in the UK BiobankDOI 10.1101/2023.10.19.23297257
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