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Article

An in vivo study on brain microstructure in biological and chronological ageing.

PloS one - 1 Jan 2015

Altmann-Schneider Irmhild, de Craen Anton J M, van den Berg-Huysmans Annette A, Slagboom Pieternella, Westendorp Rudi G J, van Buchem Mark A, van der Grond Jeroen

Abstract excerpt

This study aimed to investigate whether magnetization transfer imaging (MTI) parameters of cortical gray and white matter and subcortical gray matter structures differ between subjects enriched for human familial longevity and control subjects to provide a thorough description of the brain phenotype of familial longevity. Moreover, we aimed to describe cerebral ageing effects on MTI parameters in an elderly...

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PMID: 25807271
DOI: 10.1371/journal.pone.0120778
PMCID: PMC4373824

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MTR

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