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ExoS Effector in <i>Pseudomonas aeruginosa</i> Hyperactive Type III Secretion System Mutant Promotes Enhanced Plasma Membrane Rupture in Neutrophils

2024-01-25

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a large percentage of airway infections that cause morbidity and mortality in immunocompromised patients, especially those with cystic fibrosis (CF). One important P. aeruginosa virulence factor is a type III secretion system (T3SS) that translocates effectors into host cells. ExoS is a T3SS effector with ADP ribosyltransferase (ADPRT)...

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Literature Corpus work
e729f77c-d93b-5237-938d-a7eb00ef60d8
DOI
10.1101/2024.01.24.577040
Open publication

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ExoS Effector in <i>Pseudomonas aeruginosa</i> Hyperactive Type III Secretion System Mutant Promotes Enhanced Plasma Membrane Rupture in NeutrophilsDOI 10.1101/2024.01.24.577040
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