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Type III secretion system of <i>Pseudomonas aeruginosa</i> affects mucin gene expression via NF-κB and AKT signaling in human carcinoma epithelial cells and a pneumonia mouse model

2018-10-12

Abstract excerpt

The type III secretion system (T3SS) in Pseudomonas aeruginosa has been linked to severe disease and poor clinical outcomes in animal and human studies. Of the various T3SS effector genes, ExoS and ExoT showed mutually exclusive distributions, and these two genes showed varied virulence. We aimed to investigate whether the ExoS and ExoT effector proteins of P. aeruginosa affect the expression of the proinflammat...

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Literature Corpus work
3f49867a-f871-5e46-9714-cac1a4e409af
DOI
10.1101/442061
Open publication

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Type III secretion system of <i>Pseudomonas aeruginosa</i> affects mucin gene expression via NF-κB and AKT signaling in human carcinoma epithelial cells and a pneumonia mouse modelDOI 10.1101/442061
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