Article

Feasibility Study Utilizing NanoString’s Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett’s Esophagus FFPE Tissues

2023-11-02

Abstract excerpt

To date, characterization of the Barrett’s esophagus (BE) immune microenvironment in patients with known progression status to determine how the microenvironment may influence BE progression to esophageal adenocarcinoma (EAC) has been understudied, hindering both the biological understanding of progression and the development of novel diagnostics and therapies. Therefore, this study’s aim was to determine if highl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f1ea336c-479e-5f83-bf4b-3619cbc885b1
DOI: 10.1101/2023.11.02.565001

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Feasibility Study Utilizing NanoString’s Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett’s Esophagus FFPE TissuesDOI 10.1101/2023.11.02.565001Read

Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett’s esophagus through progression to cancerSemantic proximity Read

The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironmentSemantic proximity Read

Concerted epithelial and stromal changes during progression of Barrett’s Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysisSemantic proximity Read

High-Plex and High-throughput Digital Spatial Profiling of non-small-cell lung cancer (NSCLC)Semantic proximity Read

Identification of Spatial Proteomic Signatures of Colon Tumor Metastasis: A Digital Spatial Profiling ApproachSemantic proximity Read

Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancerSemantic proximity Read

Spatially resolved transcriptomic and proteomic profiling reveals cell interaction programs that predict Barrett’s esophagus progressionSemantic proximity Read

Multi-omics analyses reveal spatial heterogeneity in primary and metastatic oesophageal squamous cell carcinoma.Semantic proximity Read

Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesisSemantic proximity Read

Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profilingSemantic proximity Read

Immune-tumor interaction dictates spatially directed evolution of esophageal squamous cell carcinomaSemantic proximity Read

Spatial profiling of neuro-immune interactions in gastroenteropancreatic NETsSemantic proximity Read