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Accumulation of Lipid Droplets in Microglia following Neonatal Brain Hypoxia-Ischemia

2026-07-22

Abstract excerpt

<h4>Background</h4> Hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal mortality and neurodevelopmental impairments. Following brain hypoxia-ischemia (HI), microglia face substantial metabolic stress; and upon phagocytosis, they become overloaded with lipids derived from engulfed dead neurons and myelin debris. It is unclear how microglia respond to and process the lipid cargo, and whether lipid a...

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Literature Corpus work
e678cb41-d86d-5351-9eb9-2e786b6a6a80
DOI
10.64898/2026.07.18.739219
Open publication

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Accumulation of Lipid Droplets in Microglia following Neonatal Brain Hypoxia-IschemiaDOI 10.64898/2026.07.18.739219
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