Article

Human umbilical cord mesenchymal stem cells alleviate white-matter injury by regulating polarization of microglia

2025-12-01

Abstract excerpt

<title>Abstract</title> <p>The protective impact and unique mechanisms of human umbilical cord mesenchymal stem cells (HUC-MSCs) transplantation following hypoxic-ischemic (HI)-induced brain white-matter injury (WMI) were explored. To establish a WMI model, Sprague-Dawley rats with three days after birth underwent unilateral carotid artery ligation, followed by hypoxic exposure (8% oxygen and 92% nitrogen). Subse...

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Literature Corpus work: e16d5072-9088-5db0-9ff2-187c1f11e46f
DOI: 10.21203/rs.3.rs-6610727/v1

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