Article

Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

2020-05-29

Abstract excerpt

Melanoma is a benchmark of major clinical significance for cancer development with greater aggressiveness in the male than the female population. Surprisingly little is known on the role of androgen receptor (AR) signaling in the disease. Irrespectively of expression levels, genetic and pharmacological suppression of AR activity in a large panel of melanoma cells, derived from both male and female patients, suppre...

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Identifiers and source

Literature Corpus work: e550eacc-d979-5f66-b686-b5fbe48a2d06
DOI: 10.1101/2020.05.26.116665

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