Article

Role of Androgen Receptor in Melanoma: Mechanisms of Tumor Progression, Immune Evasion, and Therapeutic Implications

2025-08-04

Abstract excerpt

Melanoma is one of the most aggressive skin cancers, with increasing rates of occurrence. Although it has not traditionally been considered hormonally driven, recent evidence links androgen receptor (AR) signaling to important aspects of melanoma biology, including tumor growth, metastasis, immune evasion, and resistance to therapy. Mechanistically, AR promotes melanoma progression by activating a pro-metastatic g...

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Literature Corpus work: ecc54d3d-e677-5a76-bcfa-c3edc7a79cdc
DOI: 10.20944/preprints202508.0198.v1

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