Article

Androgen receptor activity promotes resistance to BRAF-targeted melanoma therapy

2020-08-17

Abstract excerpt

<title>Abstract</title> <p>Treatment with molecularly-targeted therapy has revolutionized cancer care, including BRAF/MEK-targeted melanoma therapy. However responses are heterogenous and frequently not long-lasting. Novel strategies to target resistance are needed. We studied a cohort of patients with resectable metastatic melanoma treated with neoadjuvant BRAF/MEK-targeted therapy (n=52) and noted a strong sexu...

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Literature Corpus work: 46f93f44-13c8-5482-bf47-225132b6593d
DOI: 10.21203/rs.3.rs-58480/v1

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