Article

Androgen receptor activity inversely correlates with immune cell infiltration and immunotherapy response across multiple cancer lineages

2024-05-14

Abstract excerpt

There is now increasing recognition of the important role of androgen receptor (AR) in modulating immune function. To gain a comprehensive understanding of the effects of AR activity on cancer immunity, we employed a computational approach to profile AR activity in 33 human tumor types using RNA-Seq datasets from The Cancer Genome Atlas. Our pan-cancer analysis revealed that the genes most negatively correlated wi...

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Literature Corpus work: ab718eab-fe29-5d46-a8e3-bcbb351cacd2
DOI: 10.1101/2024.05.08.593181

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