Article
Exploiting evolutionary herding to control drug resistance in cancer
2019-03-04
Abstract excerpt
Drug resistance mediated by clonal evolution is arguably the biggest problem in cancer therapy today. However, evolving resistance to one drug may come at a cost of decreased growth rate or increased sensitivity to another drug due to evolutionary trade-offs. This weakness can be exploited in the clinic using an approach called ‘evolutionary herding’ that aims at controlling the tumour cell population to delay or...
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Identifiers and source
- Literature Corpus work
- e5507f41-5c82-536c-920f-9ac233ab4ec1
- DOI
- 10.1101/566950