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Evolutionary rescue model informs strategies for driving cancer cell populations to extinction

2024-11-28

Abstract excerpt

Cancers exhibit a remarkable ability to develop resistance to a range of treatments, often resulting in relapse following first-line therapies and significantly worse outcomes for subsequent treatments. While our understanding of the mechanisms and dynamics of the emergence of resistance during cancer therapy continues to advance, questions remain about how to minimize the probability that resistance will evolve,...

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Literature Corpus work
24de7488-5920-5a25-aee5-aa350d575314
DOI
10.1101/2024.11.26.625315
Open publication

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Evolutionary rescue model informs strategies for driving cancer cell populations to extinctionDOI 10.1101/2024.11.26.625315
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