Article

Influenza A virus NS1 sequesters RNA:DNA hybrids to evade RNase H1-dependent innate immunity

2026-05-07

Abstract excerpt

RNA:DNA hybrids, and their aberrant accumulation, are key regulators of human genome integrity and innate immunity. Given the functional parallels and extensive interplay between the human genome and viral genetic material, RNA:DNA hybrids also have established roles during infections with DNA viruses and retroviruses. Nevertheless, the presence and consequences of RNA:DNA hybrids in RNA virus infections, which la...

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Literature Corpus work: e5411413-85c0-5645-96e4-d0ed3ffd5591
DOI: 10.64898/2026.05.04.722684

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