Article

High tissue-specificity of lncRNAs maximises the prediction of tissue of origin of circulating DNA

2023-01-21

Abstract excerpt

Several studies have made it possible to envision a translational application of plasma DNA sequencing in cancer diagnosis and monitoring. However, the extremely low concentration of circulating tumour DNA (ctDNA) fragments among the total cell-free DNA (cfDNA) remains a formidable challenge to overcome and statistical models have yet to be improved enough to become of practical use. In this study, we set about ap...

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Literature Corpus work: e525b45a-b1bc-59e1-884f-75320518406b
DOI: 10.1101/2023.01.19.524838

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