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Refined characterization of circulating tumor DNA through biological feature integration

2021-08-12

Abstract excerpt

Circulating tumor DNA (ctDNA) in blood plasma is present at very low concentrations compared to cell-free DNA (cfDNA) of non-tumor origin. To enhance ctDNA detection, recent studies have been focused on understanding the non-random fragmentation pattern of cfDNA. These studies have investigated fragment sizes, genomic position of fragment end points, and fragment end motifs. Although these features have been descr...

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Literature Corpus work
7c5b788a-7d95-5ed8-9aee-65a211e5b615
DOI
10.1101/2021.08.11.21261907
Open publication

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Refined characterization of circulating tumor DNA through biological feature integrationDOI 10.1101/2021.08.11.21261907
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