Article

Inferring expressed genes by whole-genome sequencing of plasma DNA

2016-04-20

Abstract excerpt

The analysis of cell-free DNA (cfDNA) in plasma represents a rapidly advancing field in medicine. cfDNA consists predominantly of nucleosome-protected DNA shed into the bloodstream by cells undergoing apoptosis. We performed whole-genome sequencing (WGS) of plasma DNA and identified two discrete regions at transcription start sites (TSS) where the nucleosome occupancy results in different read-depth coverage patte...

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Literature Corpus work: 411da9d2-cecd-5bd8-9c2a-a8d6208d8b25
DOI: 10.1101/049478

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