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Cell-Free DNA Fragmentomics: The Novel Promising Biomarker

12 Jan 2023

Abstract excerpt

Cell-free DNA molecules are released into the plasma via apoptotic or necrotic events and active release mechanisms, which carry the genetic and epigenetic information of its origin tissues. However, cfDNA is the mixture of various cell fragments, and the efficient enrichment of cfDNA fragments with diagnostic value remains a great challenge for application in the clinical setting. Evidence from recent years...

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PMID: 36675018
DOI: 10.3390/ijms24021503

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