Article

Extending Genome-Wide Association Studies to admixed cohorts with high degrees of relatedness

2025-06-09

Abstract excerpt

Recently admixed populations comprise a large portion of the human population worldwide, but are often excluded from Genome-Wide Association Studies (GWAS) due to analytic challenges. Our group has previously developed a local ancestry informed generalized linear model based method, Tractor , for GWAS in admixed samples, which produces accurate ancestry-specific effect sizes and boosts discovery power to identify...

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Literature Corpus work: e5251b92-c8cc-51eb-9ac0-1b079ad47495
DOI: 10.1101/2025.05.27.25328444

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