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X-Pro: A web-based tool to analyze the loss and gain of local interaction upon a point mutation on protein structures

2025-01-24

Abstract excerpt

Understanding how point mutations affect protein structures is critical for understanding their impacts on a protein’s function and, eventually their role in causing diseases or biological differences. In recent decades, structural inferences of missense mutations have gained significant attention due to their importance in understanding monogenic disorders. Making point mutations in silico is one of the simple bi...

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Literature Corpus work
e50ab707-3112-5eff-900c-e334847dfca3
DOI
10.1101/2025.01.22.634007
Open publication

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X-Pro: A web-based tool to analyze the loss and gain of local interaction upon a point mutation on protein structuresDOI 10.1101/2025.01.22.634007
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