Article

Missense mutations: Backbone structure positional effects

2024-12-24

Abstract excerpt

<h4>ABSTRACT</h4> Human diversity often manifests through single nucleotide polymorphisms (SNPs). Among these, missense mutations, or SNPs that alter amino acids, can modify a protein’s three-dimensional (3D) structure. This impacts its function and can potentially elicit diseases or affect drug interactions. Thus, understanding protein single point mutations is crucial for precision medicine, as it helps tailor...

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Literature Corpus work: ee862b1d-07fb-5dc3-884d-edf12714cbc7
DOI: 10.1101/2024.12.23.630208

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