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Article

MutationExplorer: a webserver for mutation of proteins and 3D visualization of energetic impacts.

Nucleic acids research - 5 Jul 2024

Philipp Michelle, Moth Christopher W, Ristic Nikola, Tiemann Johanna K S, Seufert Florian, Panfilova Aleksandra, Meiler Jens, Hildebrand Peter W, Stein Amelie, Wiegreffe Daniel, Staritzbichler René

Abstract excerpt

The possible effects of mutations on stability and function of a protein can only be understood in the context of protein 3D structure. The MutationExplorer webserver maps sequence changes onto protein structures and allows users to study variation by inputting sequence changes. As the user enters variants, the 3D model evolves, and estimated changes in energy are highlighted. In addition to a basic per-residue...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38647044
DOI: 10.1093/nar/gkae301
PMCID: PMC11223880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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