Article

Efineptakin alfa (NT-I7) improves overall survival and induces tertiary lymphoid structures in murine lung tumors

2025-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Tertiary lymphoid structures (TLSs) are emerging as good predictive biomarkers of response to cancer immunotherapy. However, therapeutic strategies to induce these structures are currently limited. We evaluated the therapeutic benefit of efineptakin alfa (NT-I7), a long-acting form of IL-7, and its ability to induce TLSs in a murine lung tumor model. NT-I7 improved overall survival in tumor-bear...

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Literature Corpus work: e4f52a7e-6065-518b-a48e-a014547c15f5
DOI: 10.1101/2025.09.15.676444

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