Article

GX-I7(rhIL-7-hyFc, efineptakin alfa), a long-acting IL-7, safely and effectively increased peripheral CD8<sup>+</sup>and CD4<sup>+</sup>T cells and TILs in patients with solid tumors

2024-02-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> GX-I7 (rhIL-7-hyFc, efineptakin alfa) is a hybrid Fc-fused long-acting recombinant human interleukin-7 (IL-7) developed by Genexine, Inc. with the aim of correcting T-cell deficiency, thereby strengthening the immune response to fight against cancer. This Phase 1b trial ( NCT03478995 ) was designed to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (P...

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Literature Corpus work: f04d17c8-3e16-58aa-bd60-ba088989e29e
DOI: 10.1101/2024.02.12.23299638

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GX-I7(rhIL-7-hyFc, efineptakin alfa), a long-acting IL-7, safely and effectively increased peripheral CD8<sup>+</sup>and CD4<sup>+</sup>T cells and TILs in patients with solid tumorsDOI 10.1101/2024.02.12.23299638Read

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