Article

Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer

2024-12-27

Abstract excerpt

Tertiary lymphoid structures (TLS) are organized immune cell aggregates that arise in chronic inflammatory conditions. In cancer, TLS are associated with better prognosis and enhanced response to immunotherapy, making these structures attractive therapeutic targets. However, the mechanisms regulating TLS formation and maintenance in cancer are incompletely understood. Using spatial transcriptomics and multiplex im...

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Literature Corpus work: 6c44f08b-cb3e-5807-af94-b5e7cb921fb5
DOI: 10.1101/2024.12.27.628014

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