Article

Genetic engineering of primary human mesenchymal stromal cells using the CRISPR/Cas9 synergistic activation mediator

2025-05-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Genomic editing technologies provide rich opportunities to approach inherited human diseases, but gene delivery strategies are still challenging. While engineered induced pluripotent stem cells or adeno-associated viral vectors may be associated with severe adverse effects, mesenchymal stromal cells (MSC) have abundantly been used for various cell therapeutic st...

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Literature Corpus work: e4e8e234-2489-5c4a-92e7-d6f58bb9e662
DOI: 10.21203/rs.3.rs-6470951/v1

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