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Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Improve the Engraftment of Myogenic Cells by Secreting Urokinase-type Plasminogen Activator Receptor (uPAR)

2021-05-17

Abstract excerpt

<title>Abstract</title> <bold>Background: </bold>Duchenne muscular dystrophy (DMD) is a severe X-linked recessive disease caused by mutations in the <italic>dystrophin </italic>gene. Transplantation of myogenic stem cells holds great promise for treating muscular dystrophies. However, poor engraftment of myogenic stem cells limits the therapeutic effects of cell therapy. Mesenchymal stem cells (MSCs) have been...

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Literature Corpus work: e1fae28e-0129-5d81-b8ac-9fa3879e6f6c
DOI: 10.21203/rs.3.rs-512276/v1

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