Article

Extra-hematopoietic immunomodulatory role of the SCID-susceptibility gene DOCK-2 identified by stepwise maturation of human iPSCs into clonogenic mesodermal stromal progenitors

2020-07-07

Abstract excerpt

<h4>ABSTRACT</h4> Stromal cells contribute to organ integrity as fibroblasts and to vascular stability as pericytes, in addition to their enigmatic niche function in many tissues. Their inherent immunomodulatory capacity attracted particular attention, initiating numerous clinical trials, particularly testing trophic regeneration and immunomodulation. Key stromal immune functions are still enigmatic. Here we show...

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Literature Corpus work: 1aa95f37-23e6-52cb-b83d-0d4a152cd66c
DOI: 10.1101/2020.07.07.192385

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