Article

Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

2023-07-28

Abstract excerpt

Tissue engineering strategies predominantly rely on the production of living substitutes, whereby implanted cells actively participate in the regenerative process. Beyond cost and delayed graft availability, the patient-specific performance of engineered tissues poses serious concerns on their clinical translation ability. A more exciting paradigm consists in exploiting cell-laid, engineered extracellular matrices...

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Literature Corpus work: d686875c-06b6-50b5-bcb1-40f16b021400
DOI: 10.1101/2023.07.28.550935

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