Article

Benchmarking for genotyping and imputation using degraded DNA for forensic applications across diverse populations

2024-07-03

Abstract excerpt

Advancements in sequencing and laboratory technologies have enabled forensic genetic analysis on increasingly low quality and degraded DNA samples. However, existing computational methods applied to genotyping and imputation for generating DNA profiles from degraded DNA have not been tested for forensic applications. Here we simulated sequencing data of varying qualities– coverage, fragment lengths, and deaminatio...

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Literature Corpus work: e4e89cf3-86cb-50ea-94fd-0809a9415abf
DOI: 10.1101/2024.07.02.601808

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