MetaGLIMPSE: Meta-imputation of low-coverage sequencing data for modern and ancient genomes.

Abstract excerpt

The advent of efficient and accurate imputation for low-coverage sequencing offers an unbiased alternative to SNP array imputation, increasing the accuracy of rare variant imputation across all populations. Since imputation accuracy generally increases with larger reference panels and closer ancestry match between target and reference samples, leveraging imputation from multiple reference panels improves...

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