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Beyond STRs: Integrative Forensic Genomics from MPS to Genetic Genealogy and AI-Based Prediction.

Genes - 18 May 2026

Brancato Desiree, Coniglio Elvira, Bruno Francesca, Treccarichi Simone, Vinci Mirella, Calì Francesco, Saccone Salvatore, Federico Concetta

Abstract excerpt

Recent advances in forensic genetics are rapidly transforming the field from traditional DNA profiling toward integrative and predictive genomic approaches. While short tandem repeat (STR)-based typing remains the gold standard for human identification, emerging technologies such as massively parallel sequencing (MPS), forensic genetic genealogy (FGG), and artificial intelligence (AI)-driven bioinformatics are...

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PMID: 42195036
DOI: 10.3390/genes17050580
PMCID: PMC13205221

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