Evaluation of genotype imputation using Glimpse tools on low coverage ancient DNA.

Abstract excerpt

Ancient DNA provides a unique frame for directly studying human population genetics in time and space. Still, since most of the ancient genomic data is low coverage, analysis is confronted with a low number of SNPs, genotype uncertainties, and reference-bias. Here, we for the first time benchmark the two distinct versions of Glimpse tools on 120 ancient human genomes from Eurasia including those largely from...

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• DNA, Ancient
• MAF gene
• Genetics, Population
• Genome, Human
• Genomics