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Application and potential value of genotype imputation techniques in ancient DNA research.

Yi chuan = Hereditas - 1 May 2026

Wei Wen-Qi, Cai Da-Wei

Abstract excerpt

Ancient DNA research plays a pivotal role in reconstructing history and understanding biological evolution. Modern genotype imputation techniques, which leverage reference panels to predict missing genotypes, have emerged as powerful tools for enhancing genetic information retrieval from ancient DNA. In this review, we examine state-of-the-art computational tools and algorithms-including GLIMPSE, Beagle, and...

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PMID: 42145194
DOI: 10.16288/j.yczz.25-166

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