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Predicting Physical Appearance from Low Template: State of the Art and Future Perspectives.

Genes - 5 Jan 2026

Sessa Francesco, Dervišević Emina, Esposito Massimiliano, Francaviglia Martina, Chisari Mario, Pomara Cristoforo, Salerno Monica

Abstract excerpt

Background/Objectives: Forensic DNA phenotyping (FDP) enables the prediction of externally visible characteristics (EVCs) such as eye, hair, and skin color, ancestry, and age from biological traces. However, low template DNA (LT-DNA), often derived from degraded or trace samples, poses significant challenges due to allelic dropout, contamination, and incomplete profiles. This review evaluates recent advances in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41595479
DOI: 10.3390/genes17010059
PMCID: PMC12841266

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