Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Predicting Physical Appearance from Low Template: State of the Art and Future Perspectives.

Genes - 5 Jan 2026

Sessa Francesco, Dervišević Emina, Esposito Massimiliano, Francaviglia Martina, Chisari Mario, Pomara Cristoforo, Salerno Monica

Abstract excerpt

Background/Objectives: Forensic DNA phenotyping (FDP) enables the prediction of externally visible characteristics (EVCs) such as eye, hair, and skin color, ancestry, and age from biological traces. However, low template DNA (LT-DNA), often derived from degraded or trace samples, poses significant challenges due to allelic dropout, contamination, and incomplete profiles. This review evaluates recent advances in...

Topics

Humans
Forensic Genetics
Machine Learning
Polymorphism, Single Nucleotide
Phenotype
DNA
Eye Color
Skin Pigmentation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41595479
DOI: 10.3390/genes17010059
PMCID: PMC12841266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predicting Physical Appearance from Low Template: State of the Art and Future Perspectives.PMID 41595479Read ↗

Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age.Semantic proximity Read ↗

Development and inter-laboratory evaluation of the VISAGE Enhanced Tool for Appearance and Ancestry inference from DNA.Semantic proximity Read ↗

Performance of the ForenSeqTM Imagen Kit for Forensic DNA Phenotyping Under Partial Genotyping Conditions.Semantic proximity Read ↗

DNA-based prediction of human phenotypic traits for the medico-legal and forensic purposes.Semantic proximity Read ↗

Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA.Semantic proximity Read ↗

aHISplex: an imputation based method for eye, hair and skin colour prediction from low coverage ancient DNASemantic proximity Read ↗

Forensic DNA phenotyping: Inferring phenotypic traits from crime scene DNA.Semantic proximity Read ↗

Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes.Semantic proximity Read ↗

Beyond STRs: Integrative Forensic Genomics from MPS to Genetic Genealogy and AI-Based Prediction.Semantic proximity Read ↗

Additional predictions for forensic DNA phenotyping of externally visible characteristics using the ForenSeq and Imagen kits.Semantic proximity Read ↗

Evaluation of the VISAGE basic tool for appearance and ancestry inference using ForenSeq® chemistry on the MiSeq FGx® system.Semantic proximity Read ↗

The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.