Article

Investigating the role of the RNA binding protein HuR in skeletal development and disease

2019-01-01

Abstract excerpt

Osteoarthritis is a complex multifactorial degenerative disease that is characterised by progressive loss of articular cartilage and inflammation of the synovium resulting pain and loss of mobility. HuR is a ubiquitously expressed RNA binding protein involved in the post-transcriptional regulation of target mRNAs and can reduce their rate of turnover. Previously published data suggests that HuR is spatially regula...

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Literature Corpus work: e4dd5282-c2b0-577e-b07a-a08ae6541b67
DOI: 10.17638/03040474

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