Article

Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis

2022-11-21

Abstract excerpt

<title>Abstract</title> <p>Background Upregulation of an RNA-binding protein HuR has been implicated in glomerular diseases. Herein, we evaluated whether it is involved in renal tubular fibrosis. Methods HuR was firstly examined in human kidney biopsy tissue with tubular disease. Second, its expression and the effect of HuR inhibition with KH3 on tubular injury were further assessed in a mouse model induced by...

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Literature Corpus work: f9ea23ba-af5b-5a02-9af6-8efaea89dce5
DOI: 10.21203/rs.3.rs-2180422/v1

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