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Article

HuR involvement in mitotic clonal expansion during acquisition of the adipocyte phenotype.

Biochemical and biophysical research communications - 29 May 2009

Karschner Vesna A, Pekala Phillip H

Abstract excerpt

In the nucleus HuR binds to mRNAs containing adenylate-uridylate rich elements in the 3'-untranslated region. HuR may influence expression of its ligand mRNA through regulation of polyadenylation, translocation of the message to the cytosol, stabilization of the mRNA and/or altering its translational efficiency. Suppression of HuR using siRNA resulted in an attenuation of the 3T3-L1 differentiation program,...

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Topics

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Share to 3T3-L1 Cells
Share to Adipocytes
Share to Adipogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Surface

Share to Clone Cells

Share to ELAV Proteins

Share to Mitosis

Share to RNA, Small Interfering

Source

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Identifiers

PMID: 19345675
DOI: 10.1016/j.bbrc.2009.03.152
PMCID: PMC2693087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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