Article

Transcriptional regulation of the aggrecan gene

2016-01-01

Abstract excerpt

Aggrecan is a large- aggregating proteoglycan that is essential for the function of articular cartilage. A loss of aggrecan is one of the major event in osteoarthritis, a debilitating and degenerative joint disease. To understand how a gene is lost and what fails to prevent transcription in disease state, an understanding of the bases of transcription must first be sought. Transcription is the first step in gene r...

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Literature Corpus work: b3f98597-2467-5051-946b-c35e98cf0706
DOI: 10.17638/03004940

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