Article

Cis-regulatory similarities in the zebrafish and human pancreas uncover potential disease-related enhancers

2020-04-28

Abstract excerpt

<h4>Introductory paragraph</h4> The pancreas is a central organ for human diseases that have a dramatic societal burden, such as pancreatic cancer and diabetes 1,2 . Non-coding cis-regulatory elements (CREs) of DNA control gene expression 3,4 , being required for proper pancreas function. Most disease-associated alleles 5,6 are non-coding, often overlapping with CREs 5 , suggesting that alterations in these r...

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Literature Corpus work: e4d1f73f-087e-5c30-a636-4349c6b6ea55
DOI: 10.1101/2020.04.27.064220

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