Article

Evaluation of lamin A/C mechanotransduction under different surface topography in LMNA related muscular dystrophy

2022-01-03

Abstract excerpt

Most of the single point mutations of the LMNA gene are associated with distinct muscular dystrophies, marked by heterogenous phenotypes but primarily the loss and symmetric weakness of skeletal muscle tissue. The molecular mechanism and phenotype-genotype relationships in these muscular dystrophies are poorly understood. An effort has been here to delineating the adaptation of mechanical inputs into biological re...

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Literature Corpus work: e4c1c130-9297-54b3-812b-e9e9f63b515e
DOI: 10.1101/2022.01.03.474777

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