Article

Targeting the Warburg Effect in Anaplastic and Poorly Differentiated Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic Opportunities

2026-04-23

Abstract excerpt

Anaplastic thyroid carcinoma (ATC) and poorly differentiated thyroid carcinoma (PDTC) represent the most aggressive thyroid malignancies, characterized by rapid progression, therapeutic resistance, and poor prognosis. Conventional treatments remain largely ineffective, highlighting the need for novel therapies. Metabolic reprogramming, particularly the Warburg effect (WE), has emerged as a potential therapeutic ta...

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Literature Corpus work: e498e4b8-0da5-5856-9637-92a9ee1a6189
DOI: 10.20944/preprints202604.1680.v1

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