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Article

Glucose Metabolic Reprogramming in Thyroid Cancer: Underlying Molecular Mechanisms and Links to Progression and Treatment.

Current medical science - 1 Jun 2026

Zhang Yi-Meng, Zeng Xin-Yu, Wang Yuan, Yang Chen, Bai Jian-Qi, Wang Jian-Peng, He Shan, Zhang Ping

Abstract excerpt

Thyroid cancer (TC) is a common endocrine malignancy with rapidly increasing global incidence. Clinical management remains challenging for advanced and radioiodine-refractory thyroid cancer (RAIR-TC). Metabolic reprogramming, especially enhanced aerobic glycolysis (the Warburg effect), is a core hallmark of TC that drives tumor progression and therapeutic resistance. This review systematically summarizes the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

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Source

Identifiers

PMID: 42126497
DOI: 10.1007/s11596-026-00206-8

Genes

BRAF
HK2
LDHA
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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