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Article

Oncogenic mutation-driven metabolism-immunity regulatory axis: Potential prospects for thyroid cancer precision therapy.

Biochimica et biophysica acta. Reviews on cancer - 1 Nov 2025

Zhang Tingting, Han Hengtong, Zhang Tianying, Zhang Yating, Ma Libin, Yang Ze, Zhao Yong-Xun

Abstract excerpt

Oncogenes enhance cancer development, and their specific activating mutations exemplify the mechanisms that initiate and mediate thyroid cancer (TC) progression. Research has predominantly focused on how oncogenes promote the development of different TC subtypes by influencing the downstream signaling pathways. Targeted therapies show significant efficacy; however, they often induce drug resistance through...

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PMID: 41005624
DOI: 10.1016/j.bbcan.2025.189459

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